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Gradual dose reduction is not typically necessary with Rybelsus from a safety perspective, as there is no specific withdrawal syndrome
Your weight If you are obese and have a higher body mass index, you may need tirzepatide treatment for a longer time and at higher doses (if your body tolerates it) compared to those with a lower body mass index or those who are a bit overweight
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Schiesser adds that herbal supplements, such as slippery elm and fennel seed, can help with dyspepsia, too
Potential metabolic benefits: As a vitamin B3 derivative, niacinamide itself has some metabolic effects that may complement tirzepatide's action