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Future directions include the need for well-designed RCTs with large sample sizes to confirm findings, assessment of long-term safety and tolerability in patients with HS, and further research into the molecular mechanisms by which GLP-1 RAs affect HS pathophysiology

As a result, clinicians are shifting toward integrative strategies that prioritize the root cause over symptomatic quick fixes

This means the salivary glands dont have enough raw material with which to create saliva

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