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CB-839, a GLS inhibitor that blocks the conversion of glutamine into glutamate, reduced the production of R-2-HG in AML cell lines and patient tissues harboring IDH1/2 mutations 123

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Peer review Peer review information Nature Reviews Endocrinology thanks Steven Heymsfield, Luis Moreno and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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Lim B, Meyer AJ, Cobbett CS (2011) Development of glutathione-deficient embryos in Arabidopsis is influenced by the maternal level of glutathione