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CrossRef NSD2 exacerbates metabolic dysfunction-associated steatotic liver disease progression by suppressing TFEB-mediated autophagy-lysosomal pathway Yuan Qiao, Yijia Zhang, Cuiting Sun, Qi Jin, Peng Qu, Zecheng Li, Yang Qiu, Hua Meng, Dantao Peng, Liang Peng Metabolism .2026

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NRF-2 possesses six Neh (NRF2-ECH homology) domains, in which Neh1 is a bZIP structure that works for the dimerization of NRF-2 and its binding to DNA [17]

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Weight loss and the use of GLP-1RAs are contraindications in individuals with atypical anorexia nervosa, even for those with a BMI in the overweight or obese range

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The study involved data from 16,827 patients evaluated by neuro-ophthalmologists, and focused on patients with type 2 diabetes or those who were overweight or obese, comparing those prescribed semaglutide to those using non-glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications

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ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

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