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Heating tomatoes for about 15 minutes can increase lycopene concentration by up to 170%

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Free radicals are molecular entities containing at least one unpaired electron

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These include the generation of reactive oxygen species and pro-inflammatory mediators, activation of immune responses, stimulation of both angiogenesis and lymphangiogenesis, alterations in myocardial electrophysiology, and induction of cellular apoptosis [84]

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