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Of the 14 semaglutide-treated patients that developed anti-semaglutide antibodies, 7 patients (0.2% of the overall population) developed antibodies cross-reacting with native GLP-1
This genetic issue caused differences in both weight loss and side effects
This is why tirzepatide is sometimes described as a "dual agonist." It's not simply a stronger version of semaglutide
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Additionally, function and expression of Na/H exchanger isoform 3 (NHE3) decreased but there was increased urine flow and sodium excretion in the tested young SHRs
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