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The spinal cord and peripheral nerves
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Yes, by regulating melanin production and reducing oxidative stress, it may help improve melasma appearance
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PAs beneficial effects might be attributed to iron chelation, decreased CYP2E1 mRNA expression, increased SIRT -1 expression at both mRNA and protein levels, and decreasing oxidative stress
Similarly, thioctic acid (10300 mg/kg) induced a graded antiallodynic response
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