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After six months, a significant improvement in hyperpigmentation was noted by the patient and physician with near clearance of hyperpigmentation (Figure 1)

[20] [21] [22] Bacteria [edit] Human white blood cells use enzymes such as NADPH oxidase to generate superoxide and other reactive oxygen species to kill bacteria

If youve missed more than 2 weeks worth of the medication, its important to contact your doctor or pharmacist

The unabsorbed residues deposit in the intestine, which forces the intestinal mucosa to fill with large quantities of black or brown pigment.31 The use of anthraquinone laxatives can result in the displacement of electrolytes and water loss in the intestinal tract and sequentially lead to the deposition of protein products after using such laxatives for a long period