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Although the overall number (frequency) of Tregs may be unchanged in MS patients compared to controls, studies indicate that their inhibitory function is impaired, which correlates with diminished immune control in vivo ( Further studies have shown the absence of GSH in T cells does not interfere with TCR signaling but leads to a failure to reprogram cellular processes needed for robust clonal expansion and prevents the induction of aerobic glycolysis and the increase in cell size associated with T cell activation (Klein Geltink et al., 2017)

Yang et al., 2013

2000 Jul;38(7):625-34 No Abstract [3] Kidd PM

Your metabolism, stress levels, and how well you take care of yourself between treatments all play a role too

Within this complex network of cells and molecules, glutathione emerges as a critical player, exerting powerful effects on immune function

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