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For non-diabetics, repeat at 6 months to assess metabolic improvement

Nutritional management may therefore be more appropriately framed as stabilization of rate-limiting metabolic modules rather than post hoc correction of overt deficiency (Fig

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[2] Ongoing research comparing various long-acting estrogen esters suggests that estradiol cypionate provides a favorable pharmacodynamic window, but head-to-head trials remain limited and further study could clarify dosing equivalencies in diverse patient populations

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