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Look for glycerin, hyaluronic acid, aloe vera, panthenol, or ceramides
Key finding: AOD 9604 increased type II collagen synthesis by 180% and cartilage proteoglycan content by 156% in human OA chondrocytes
"Photoaging therapy with topical tretinoin: an evidence-based analysis." Journal of the American Academy of Dermatology
If fatigue continues, a clinician may evaluate anemia, thyroid disease, sleep problems, medication effects, mood concerns, or other causes
And multi-level anti-inflammatory modulation reduces damaging cytokines like IL-6 and TNF-alpha
The peptide acts as a catalyst, not a substrate
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