(2000), Horm Res 53(Suppl 3), PubMed 10971106 Statistics from preclinical literature AOD-9604 = modified fragment of hGH 177191 + N-terminal Tyr (sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe), molecular weight 1815.1 Da Developed at Metabolic Pharmaceuticals (Australia) based on the work of professor Frank Ng (Monash University) in the 1990s Standard experimental dose in obesity clinical trials: 1 mg/day subcutaneously (Phase 2b, Heffernan et al.) Mechanism: stimulation of 3-adrenergic receptors in adipose tissue, increased lipolysis and fatty acid oxidation without activation of the hGH receptor (no IGF-1 increase) Phase 2b clinical trial (2007, 300 patients): weight reduction ~2.8 kg vs placebo over 12 weeks FDA status: NDI rejection (2014) as a dietary supplement
Food and Drug Administration (FDA) for human use or medical application
AOD-9604 is a modified fragment of human growth hormone (specifically amino acids 176-191) that was developed to isolate the fat-reducing properties of growth hormone while eliminating the metabolic side effects
The substance is classified as a non-Specified Substance, and detection in an athlete's sample carries the standard four-year sanction for a first offence
RUO product-page language should keep published research findings separate from product effects, product performance, or any consumer-facing interpretation
It's important to handle this medicine responsibly to avoid overdosing