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Vital signs including blood pressure, heart rate, and body temperature remained stable
In another study, researchers discovered that tirzepatide treatment, when combined with a decrease in circulating levels of branched-chain amino (BCAA) and keto (BCKA) acid metabolites linked to the development of systemic insulin resistance (IR) and T2DM improves insulin sensitivity in obese mice and humans with T2DM [82]
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A MASLD substudy within the phase 2 obesity trial of retatrutide provided compelling evidence of hepatic benefits
