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93 Additionally, tirzepatide, a dual GIP/GLP-1 receptor agonist, has gained prominence following USFDA approval in 2023 for weight management in adults with obesity or overweight and has demonstrated robust efficacy in RCTs

Persistent or severe nausea should be medically evaluated

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The metabolic effect continues driving weight loss, but the body adapts to the new baseline similar to how side effects like nausea typically improve after the initial dose escalation phase

Some of the GLP-1s approved to treat T2D, such as Ozempic, are also widely known to be used for weight loss