Theres a great risk of muscle loss and malnutrition They can interfere with the absorption of other meds, including psychiatric meds Some people wont lose any weight at all Most people will regain weight after they discontinue use (as is the case with any diet) Theres limited long term research and a whole bunch of misinformation They can alter taste perception and decrease the enjoyment of eating So we know they can help with diabetes, theres a long list of risks and more we dont know, and at the same time some people have found GLP-1s offer the potential to re-connect with internal signals and eventually help build body trust
Environ Exp Bot 61:8593 Tamaoki M, Matsuyama T, Nakajima N, Aono M, Kubo A, Saji H (2004) A method for diagnosis of plant environmental stresses by gene expression profiling using a cDNA macroarray
Current Urology, 15 (2), 95100
A large observational study published in Diabetologia in 2022 looked at GLP-1 receptor agonist use in humans and found no statistically significant increase in thyroid cancer risk
Prog Mol Biol Transl Sci 131:119146
Berberine is a potential therapeutic drug for alleviating motor dysfunction and memory impairment in patients with Parkinsons disease (Kim et al., 2014)