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We have preliminary evidence that transmission of pathology recapitulating abnormalities found in non-lesional MS NAWM occurs in humanized transgenic mice after intracerebral inoculation with MS brain homogenates (Tsutsui et al., 2019)
Microbial consortia involved in fermentation and gut symbiosis are capable of synthesizing substantial amounts of vitamins B, C, and K, and actively participate in the breakdown of anti-nutritional compounds such as phytic acid, thereby increasing the bioavailability of essential compounds that would otherwise be poorly absorbed (99)
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