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Some have to hold the current dose longer or reduce it for a while

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A review, Obesity Pillars (2023) Why does obesity cause diabetes?, Cell Metabolism (2022) Obesity, insulin resistance, and Type 2 diabetes: associations and therapeutic implications, Diabetes, Metabolic Syndrome, and Obesity (2020) Diabetes and polycystic ovary syndrome (PCOS), Centers for Disease Control and Prevention (2024) Higher risk of type 2 diabetes in young women with polycystic ovary syndrome: A 10-year retrospective cohort study, World Journal of Diabetes (2022) Obesity and polycystic ovary syndrome, Obesity Management (2010) What is metabolic syndrome?, National Heart, Lung, and Blood Institute Weight loss from combination anti-obesity medication regimens can approach that achieved from bariatric surgery, JCEM Case Reports (2023) Phentermine patient information, American Association of Clinical Endocrinology (2013) Hypoglycemia (low blood sugar), Cleveland Clinic (2023) Phentermine label, Teva Pharmaceuticals USA (2012) Pharmacologic treatment of overweight and obesity in adults, Endotext (2000) Glucophage (metformin) label, Bristol-Myers Squibb Company (2017) Phentermine hydrochloride tablet, DailyMed (2018) Metformin hydrochloride tablet, DailyMed (2021) Lists of scheduling actions, controlled substances, regulated chemicals, Drug Enforcement Administration (2024) Metformin: When should we fear lactic acidosis?, International Journal of Molecular Sciences (2022) FDA revises warnings regarding use of the diabetes medicine metformin in certain patients with reduced kidney function, Food and Drug Administration (2016) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice

Protocols vary by route no single standardised regimen

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