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Seiler A, Schneider M, Frster H, Roth S, Wirth EK, Culmsee C et al (2008) Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent-and AIF-mediated cell death

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The ability to selectively induce apoptosis in MDSCs through TRAIL-R1 and TRAIL-R2 activation provides a unique opportunity to dismantle the immunosuppressive TME