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This metabolic imbalance makes the inefficiencies related to fatty acid oxidation even worse and contributes to overall metabolic disorder in the hearts of diabetic patients (54)
Discontinuation rates from the phase 2 trial due to side effects were generally low, though the broader literature on GLP-1 receptor agonists notes that discontinuation rates across the class can reach 20-50% within the first year
Products and compounds referenced are for research use only and are not approved for human or veterinary consumption
However, more research is needed to move from speculation to treatment
The committee voted in favor of adding BPC-157, a step that may eventually open the door to legal prescribing and compounding
The role of adherence and persistence is beyond the scope of this study, but a promising area of further research is to explore which patients may benefit from this medication class, and how to ensure that the benefits of GLP-1 medications are fully realized in a real-world setting by addressing adherence challenges
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