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In adults (offlabel): may support favorable changes in body composition, energy, recovery, and metabolic markers (evidence limited

These shifts can trigger complicated emotions, including grief over lost time or anxiety about maintaining progress

In RCTs of FGF21 analogues in participants with MASH, the most common adverse events reported were nausea, diarrhoea and injection site erythema [48, 49]

There were insignificant differences in recurrent myocardial infarction (MI) or all- cause deaths

Donnan K et al