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At this stage, the old equation calories in versus calories out becomes an oversimplification, because the metabolic thermostat has been raised

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Many thermostats, weather stations, and even some smart speakers log ambient temperature throughout the day

It mimics a natural gut hormone called glucagon-like peptide 1, which the body releases after meals to signal fullness, slow stomach emptying, and stabilize blood sugar

Despite the very low absolute risk for ischemic optic neuropathy, the rapidly expanding use of GLP-1 receptor agonists in patients with and without type 2 diabetes increases the clinical and public health importance of any potential association, conclude the authors