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In contrast, GCLC inhibition exerted a minimal impact on the growth of PDX tumors with low ACTL6A expression (cases 2 and 4) tumors (Fig

Data are means+SEM of 3 independent experiments, each performed in triplicate

Normally, acetaldehyde is quickly converted into less harmful substances, but impaired acetaldehyde metabolism can lead to alcohol metabolite accumulation

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Estrogen levels, then these lesions can't proliferate