The Bigger Concern: Leaving a Deficiency Untreated When weighing the minimal risks of B12 injections, it helps to consider the well-documented risks of an untreated B12 deficiency
But for the right person, they offer real support sharper focus, steadier energy, a metabolic nudge that makes other efforts pay off faster
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Insufficient B12 can damage the myelin sheath, leading to nerve degeneration and cognitive issues
However, preclinical safety studies report no major toxicity across animal studies (mice, rats, rabbits, dogs) and showed no adverse effects across several organ systems
in total, 9 genera (including the unclassified group) and 38 metabolites met these criteria (metabolites published in Sampson et al., 2021 13 )