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In the animals, the fetal complications happened when mothers did not gain weight or lost weight during their pregnancies

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Researchers are looking into the behaviour of GIP receptors to see what part they might play in how insulin works and how energy is used

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For the mitochondrial OCR assays, mitochondria were plated on Seahorse Biosciences 96-well culture plates (5 g of protein per well) and centrifuged for 20 min at 2,000 g at 4 C to adhere mitochondria to the base of wells

Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease