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FiorelliSPorroBCosentinoNDi MinnoAManegaCMFabbiocchiFet alActivation of Nrf2/HO-1 pathway and human atherosclerotic plaque vulnerability: an in vitro and in vivo study
it does not mean senolytics cause cancer, but it highlights that the biology of senescence is not uniformly harmful and that senolytic intervention requires careful therapeutic window definition
The benefits continue to improve for several months
It is guesswork
The affected enzymes, ERK1/2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, are believed to play significant roles in cell growth, migration, and angiogenesis, which is the development of new blood vessels
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