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(2) ROS accumulation builds sleep pressure sensed in specific neurons that promote sleep, which in turn dissipate ROS burden and return the mitochondrial NAD + /NADH ratio to baseline (Kempf et al
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The fluorescence intensity was assayed by an FV10i laser scanning confocal microscope (Olympus, Tokyo, Japan)
Perspect Biol Med 41(3):359390
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As research into the metabolic vulnerabilities of cancer cells continues to evolve, the kynurenine pathway will likely remain a key target for future therapeutic interventions
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