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Authors: Thomas Kruse, Jakob Lerche Hansen, Kirsten Dahl, Lauge Schffer, Ulrich Sensfuss, Christian Poulsen, Morten Schlein, Ann Maria Kruse Hansen, Claus Bekker Jeppesen, Charlotta Dornonville de la Cour, Trine Ryberg Clausen, Eva Johansson, Simone Fulle, Rikke Bjerring Skyggebjerg, Kirsten Raun URL: This paper details the medicinal chemistry efforts that led to the design and synthesis of cagrilintide, a long-acting amylin analogue for the treatment of obesity
*Correspondence: Bin Chen [email protected] This article was submitted to Food Chemistry, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
In its reduced form (GSH), it neutralizes reactive oxygen and nitrogen species and participates in enzyme systems that protect cellular structures, DNA, and extracellular matrix components from oxidative damage
use of supplements containing glutathione and/or other antioxidants within one month prior to the study
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doi: 10.1111/dom.12639 84 ManigaultKRThurstonMM
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