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Intriguingly, studies suggest a potential role of GLP-1 RAs in pain relief, including acute and chronic pain 65 , chronic migraine 66 , and diabetic neuropathic pain 67
9 , 447s454s (2003)
To overcome these limitations, novel drug delivery systems have been developed most recently, including nano- and micro-carrier-based delivery systems, hydrogels, microneedle-based transdermal delivery systems, and enhanced longer-acting or combined formulations
Blher, C.K
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