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May 2024;8(5):e13066

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The screen was performed once for hit identification

Spermidine also blocks Akt activity, while UroA inhibits PI3K activity, which can activate Akt (Reference Niu, Jiang and Guo36Reference Hofer, Simon and Bergmann39)

(bipartite) chemical synapse when a chemical ( neurotransmitter ) transduces an electrical impulse into chemical information ( receptor binding ) via a gap between a presynaptic and a postsynaptic neuron ( synaptic cleft )