[PMID: 7820668] PubMed record related to this compound for laboratory literature review
While HGH has systemic regenerative benefits, it is an indirect mechanism
Source data Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made
Therefore, external validation trials with larger cohorts are essential
Restoring mitochondrial function, inhibiting apoptosis, and downregulating ROS accumulation were the mechanisms that brought about this protection
In vivo, GCLC overexpression significantly mitigated MPTP-induced motor deficits and dopaminergic neuron loss in mouse models