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Chronic activation of microglia is associated with protein degradation, mitochondria dysfunction, and defects of axonal transport and apoptosis, which adversely affect neuronal function and lead to cell death (49)

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Dextromethorphan, a key ingredient, exhibits psychoactive properties that lead to dependency

doi: 10.1210/en.2017-00812 157 GuGRolandBTomaselliKDolmanCSLoweCHeiligJS