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Wexler 2021a)
Serious vitamin B12 deficiency may result in a low number of red blood cells (anemia), stomach/intestine problems, and permanent nerve damage.Niacinamide (nicotinamide) is a form of vitamin B3 (niacin) and is used to prevent and treat niacin deficiency (pellagra)
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As expected, and consistent with a reduced interaction of the amidated C-terminal tyrosine with the CTR ECD, CagriP37Y presented a lower potency than Cagri in cells expressing CTR alone (Supplementary Fig
