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J Clin Chem Clin Biochem
Manufacturers demonstrating bioequivalence in a single Phase 3 trial (rather than the traditional two trials) can achieve interchangeable status, allowing pharmacy-level substitution without prescriber intervention
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If it is not easing at a stable dose, or it is getting worse rather than better, that is worth raising rather than absorbing
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ONOO- inhibits Na-alanine co-transport ( ASCT1 ) by reducing its affinity for alanine and Na-glutamine co-transport ( B0AT1 ) by decreasing co-transporter numbers, revealing potential mediation of NaAAcT alterations in inflammation (152)
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