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We collected single particle datasets from the purified DDD-Ube2e2-COP1-c-Jun sample (Supplementary Table 3)

The actin-binding region itself has been linked to vascular activity: a 2003 study in the FASEB Journal reported that the site promoting actin interaction is also associated with angiogenic activity in experimental models

This work lays a solid foundation for the development of sequential therapeutic agents that target vascular repair and provides robust scientific evidence to optimize strategies for the prevention and treatment of tissue injury across various contexts

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JAMA 306 , 15491556 (2011)