Lancet 2020;395:1988-97
Chen M, Zhang X, Lee YS et al (2015) Bioavailability challenges of Spiraeoside: Enhancing therapeutic potential through advanced delivery systems
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It is currently the phase II drug associated with the greatest weight reduction, achieving a 24% decrease (28.5% in women) after 48 weeks with a weekly dose of 12 mg55 (Table 1), and providing significant benefits in the control of cardiovascular risk factors and the reduction of MASLD56 (Fig