This pattern reflects the chronic, relapsing nature of obesity and has prompted the WHO to recommend continuous, long-term treatment lasting six months or moreeffectively positioning these medications as lifetime therapies for many patients [51]
Prescribing GLP-1s: Evidence, limits, expectations How physicians integrate GLP1s into long-term weight management GLP-1 medications are reshaping the conversation around metabolic health and weight loss but questions remain
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25 Although data from clinical studies on liraglutide revealed a 7% increase in serum amylase and a 31% increase in serum lipase in patients after four weeks of GLP-1 receptor agonist treatment compared with placebo, the increased levels reverted to normal once therapy was discontinued and did not predict acute pancreatitis onset