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Conditions affecting the small intestine, such as malabsorption syndromes (celiac disease and tropical sprue), may also result in vitamin B 12 deficiency
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Ods.od.nih.gov
people at higher risk of deficiency include older adults, those with gastrointestinal issues that impair absorption, people whove had gastric surgery, long-term strict vegans who do not supplement, and those on certain acid-reducing medicines
It is studied in mice, preclinical models, and referenced in clinical trials and clinical evidence to understand metabolic function, IGF 1 levels, and IGF 1 LR3 interactions
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