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Overall, whilst these findings imply that increased production of ROS is associated with C9orf72-ALS, it is unclear whether loss of C9orf72 or expression of hexanucleotide repeat expansions disturbs redox homeostasis
Some patients may need additional evaluation or labs depending on symptoms, history, and the clinician's judgment
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Kirkman, H
This is the same additional pathway that tirzepatide uses beyond semaglutide
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