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References: Adrian S, Scherzinger A, Sanyal A, Lake JE, Falutz J, Dub MP, Stanley T, Grinspoon S, Mamputu JC, Marsolais C, Brown TT, Erlandson KM
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Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4
More recently, agents within the GLP-1 receptor agonist class have also demonstrated cardiovascular and kidney benefits in completed cardiovascular outcome trials
GO over-representation analyses used clusterProfiler::enrichGO (one-sided hypergeometric test), BH-adjusted