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Lifestyle modifications that may help include wearing loose, soft-textured clothing made from natural fibers, using silk or satin bedsheets that produce less friction, maintaining a consistent room temperature to avoid thermal triggers, practicing stress reduction techniques since psychological stress can amplify central sensitization, and optimizing sleep hygiene since poor sleep worsens pain perception

PubMed laboratory research record [PMID: 28434490] PubMed record related to this compound for laboratory literature review

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Basic dosage: 2.5-3.75 micrograms/kilogram of body weight/time/twice a day