The effects of feed restriction during organogenesis on embryo-fetal development in the rat
On day -6, mice were randomized into four groups (n = 12/group): vehicle (PBS), or MEDI4166 (3, 10 or 30 mg/kg)
Individual variation is significant based on compliance, starting composition, and metabolic response
The compound has since remained an active subject of preclinical research, particularly in the areas of lipid metabolism, adipose tissue signaling, and exploratory tissue repair models
Hair shedding may start weeks or months after fast weight loss begins, which can be confusing
Managing blood sugar, maintaining a healthy diet, and using medications as prescribed can help minimize hair thinning related to diabetes