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Durable vision improvement after a single intravitreal treatment with antisense oligonucleotide in CEP290-LCA: replication in two eyes

The manufacturer's stability data shows semaglutide maintains full potency for up to 28 days once opened when kept at the correct refrigeration range

Binding to this allosteric site can still influence the sensitivity and activity of the receptor, but could lead to drugs with fewer off-target side-effects, since GLP-1 is involved in many different metabolic signalling pathways