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Phenome-wide associations In the GWAS catalogue 18 , the index BMI-loss SNP in GLP1R , rs10305420, has been reported as associated with T2D 19,20 , smoking initiation 21 , fasting glucose 20 and haemoglobin A1c (HbA1c) measurements 20
While more studies are needed, this could be an exciting avenue for future weight management strategies
OGrady, G., Wang, T
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