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10.1517/13543780903463862 37 DeaconC

FMR1, Fragile X Messenger Ribonucleoprotein 1

By attaching to estrogen receptors on cancer cells, tamoxifen prevents estrogen from binding to them, which can slow or stop the growth of the cancer cells

The charged amino group of the glutamic acid moiety forms stable interactions with D167, R177, and I179

It is also almost impossible to determine whether the oral mucosal melanin hyperpigmentation in an HIV-seropositive smoker who is on multiple drug therapy is owing to the medication, to the HIV infection, to the use of tobacco, or to the interaction between these factors

Erring on the side of caution is appropriate