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sALS and fALS share several features, including protein aggregation, motor neuron hyperexcitability, trafficking defects, disruption of nucleocytoplasmic transport, oxidative stress, mitochondrial dysfunction, glutamate excitotoxicity, and neuroinflammation

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After adjusting for patient characteristics, semaglutide treatment showed a gastroparesis risk 3.33 times higher than bupropion-naltrexone and 6.14 times higher than sleeve gastrectomy [4]

In patients with metabolic dysfunction-associated steatotic liver disease (MASLD), more than 85% experienced resolution of liver fat accumulation, with reductions of over 70% in fat content