appeals for gip glp 1 Gastrointestinal Incretins—Glucose-Dependent Insulinotropic Polypeptide (GIP) and Glucagon-like Peptide-1 (GLP-1) beyond Pleiotropic Physiological Effects Are Involved in Pathophysiology of Atherosclerosis and Coronary Artery Pretoria pharmacy group iDexis says

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doi:10.1016/j.steroids.2007.08.001

Blood sugar fluctuations, insulin resistance, and mitochondrial strain increase: Oxidative stress Pro-inflammatory cytokine signaling Nervous system reactivity Impaired cellular recovery Even subtle metabolic instability can make pain more persistent and resistant to conventional treatment

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Li GF, Zhao M, Zhao T, Cheng X, Fan M, Zhu LL (2019) Effects of metformin on depressive behavior in chronic stress rats

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