The FDA prescribing information includes a boxed warning about thyroid C-cell tumors observed in animal studies
It also minimizes the activity of free radicals in the body, preventing the activation of melanin-producing enzymes
Fineman MS, Shen LZ, Taylor K, Kim DD, Baron AD
However, I believe a far more effective way to activate AMPK is using Metabolic Engineering, not only to avoid the side effects of current GLP-1 drugs, but also to achieve far greater metabolic control
Sequence clinicians used to check their eligibility for using GLP-1 medications such as semaglutide after assessing their body mass index, blood sugar levels, medical history, and comorbid conditions
PMID 15822171