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In reality, it's the physical symptom of the underlying metabolic problem, and that's what these drugs address, he says

Christ-Hazelhof E et al

Medication, Prescription Drug, and Topical Product Interactions Topical GHK-Cu may interact practically with other skin products by increasing irritation risk, especially in people using retinoids, acids, exfoliants, medicated creams, or post-procedure regimens

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It has also been demonstrated that ERs are pivotal in the maintenance and functioning of oligodendrocyte progenitor cells (OPCs) and post-mitotic oligodendrocytes (OLs), respectively

Published literature going back decades doesn't show significant adverse effects at typical doses