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10.1111/j.1365-3059.2010.02340.x 82 KovtunY.ChiuW

J.WallerM

This synergistic blend combines three peptides targeting body composition: AOD-9604 (hGH fragment 177191) promotes lipolysis without raising IGF-1 [1]

GLP-1, GIP and glucagon triple agonism reduced body weight and blood glucose levels in diet-induced obese mice to a higher extent than monoagonists and dual GLP-1/GIP receptor agonists [94]

This likely explains why two agonists at the same receptor produce different physiological profiles

Brainimaging studies suggest GLP-1 medications can dial down how strongly the brain reacts to highcalorie food cues, so those foods feel less compelling rather than simply making people less hungry in general