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The DPP-4 inhibitor linagliptin restores -cell function and survival in human isolated islets through GLP-1 stabilization
Therefore, we concluded that GSDMD deficiency aggravated perfusion recovery, while CCL11 induced by GSDMD has a protective effect against perfusion recovery impairment by improving angiogenesis
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Moreover, metformin can directly protect endothelial cells from injury, which is beyond its glucose-lowering effects 7,8
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By influencing these pathways, retatrutide aids blood sugar regulation and facilitates weight loss
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